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| Definition: | An inherited type of heart disease where there are defects in the internal walls (septa) between the atrium and ventricle chambers of the heart. Holt-Oram syndrome is dominant (requires only one copy in the genome to be expressed) and is often associated with skeletal deformities such as abnormally short forearms or thumbs. | ||
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| Synonyms: | Holt-Oram syndrome | ||
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